Andrew Christian started the clothing line in 1997. He sold his clothing in local boutiques. He chose a generic cross icon for his logo as he wanted to avoid religious connotations. The regular fashions were followed, over the years, by sportswear, swimwear, and then underwear, "and that's when things really took off.” In 2006, with the addition of the underwear lines, sales grew exponentially. In the 2007/2008 season they did an Obama underwear, donating $1 from every sale to the 2008 Barack Obama Presidential Campaign.

In the 2008/2009 season the company started making clothes for women as well as men. In 2013 they expanded the sportswear lines.